A Deep Learning Algorithm For Classification Of Oral Lichen Planus Lesions From Photographic Images: A Retrospective Study

  1. Study Design and Data Collection

    • The study protocol was approved by the Marmara University School of Medicine Non-Interventional Clinical Research Ethics Committee.
    • Photographic images of buccal mucosa with healthy and oral lichen planus lesions were collected using the CranioCatch program.
    • The dataset was divided into training, verification, and test sets for both healthy mucosa and mucosa with oral lichen planus lesions.
  2. Identification of Disease Features

    • Oral lichen planus exhibits clinical findings ranging from reticular white plaques to mucosal erythema, erosions, ulceration, and hyperkeratotic plaques.
  3. Deep Convolutional Neural Network Architecture

    • The deep learning process utilized the GoogleNet Inception V3 architecture implemented with the Tensorflow library.
    • The architecture involved changing the filter size and grid size to improve efficiency in processing the images.
  4. Results of the Deep Learning Algorithm

    • The AI deep learning model correctly classified all test photos for both healthy and diseased mucosa.
    • The accuracy of the model in distinguishing between normal buccal mucosa and oral lichen planus lesions was 100%.
  5. Significance and Future Implications

    • The study presented a novel deep learning algorithm for the classification of oral lichen planus lesions from photographic images in Turkey.
    • The findings suggest that deep learning has the potential to address the challenge of diagnosing oral lichen planus accurately.
    • Future AI developments in healthcare should prioritize human interests as a core goal, aiming to improve diagnostic abilities and patient outcomes.